Anti-infective Drugs
/ infective drugs books
Anti-infective drugs are classified as antibacterials,
antivirals, or antifungals depending on the type of microorganism
they combat. Anti-infective drugs interfere selectively with the
functioning of a microorganism while leaving the human host unharmed.
Antibacterial drugs, or antibiotics-sulfa drugs, penicillins, cephalosporins,
and many others-either kill bacteria directly or prevent them from
multiplying so that the body's immune system can destroy invading
bacteria. Antibacterial drugs act by interfering with some specific
characteristics of bacteria. For example, they may destroy bacterial
cell walls or interfere with the synthesis of bacterial proteins
or deoxyribonucleic acid (DNA)-the chemical that carries the genetic
material of an organism. Antibiotics often cure an infection completely.
However, bacteria can spontaneously mutate, producing strains that
are resistant to existing antibiotics.
Antiviral drugs interfere with the life cycle of a virus by preventing
its penetration into a host cell or by blocking the synthesis of
new viruses. Antiviral drugs may cure, but often only suppress,
viral infections; and flare-ups of an infection can occur after
symptom-free periods. With some viruses, such as human immunodeficiency
virus (HIV), which causes acquired immunodeficiency syndrome (AIDS),
antiviral drugs can only prolong life, not cure the disease.
Vaccines are used as antiviral drugs against diseases such like
mumps, measles, smallpox, poliomyelitis, and influenza. Vaccines
are made from either live, weakened viruses or killed viruses, both
of which are designed to stimulate the immune system to produce
antibodies, proteins that attack foreign substances. These antibodies
protect the body from future infections by viruses of the same type.
Antifungal drugs selectively destroy fungal cells by altering cell
walls. The cells' contents leak out and the cells die. Antifungal
drugs can cure, or may only suppress, a fungal infection.
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