Anti-infective
Drugs
Anti-infective
drugs are classified as antibacterials, antivirals, or antifungals
depending on the type of microorganism they combat. Anti-infective
drugs interfere selectively with the functioning of a microorganism
while leaving the human host unharmed.
Antibacterial drugs, or antibiotics-sulfa drugs, penicillins,
cephalosporins, and many others-either kill bacteria directly
or prevent them from multiplying so that the body's immune
system can destroy invading bacteria. Antibacterial drugs
act by interfering with some specific characteristics of bacteria.
For example, they may destroy bacterial cell walls or interfere
with the synthesis of bacterial proteins or deoxyribonucleic
acid (DNA)-the chemical that carries the genetic material
of an organism. Antibiotics often cure an infection completely.
However, bacteria can spontaneously mutate, producing strains
that are resistant to existing antibiotics.
Antiviral drugs interfere with the life cycle of a virus by
preventing its penetration into a host cell or by blocking
the synthesis of new viruses. Antiviral drugs may cure, but
often only suppress, viral infections; and flare-ups of an
infection can occur after symptom-free periods. With some
viruses, such as human immunodeficiency virus (HIV), which
causes acquired immunodeficiency syndrome (AIDS), antiviral
drugs can only prolong life, not cure the disease.
Vaccines are used as antiviral drugs against diseases such
like mumps, measles, smallpox, poliomyelitis, and influenza.
Vaccines are made from either live, weakened viruses or killed
viruses, both of which are designed to stimulate the immune
system to produce antibodies, proteins that attack foreign
substances. These antibodies protect the body from future
infections by viruses of the same type.
Antifungal drugs selectively destroy fungal cells by altering
cell walls. The cells' contents leak out and the cells die.
Antifungal drugs can cure, or may only suppress, a fungal
infection.
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